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Index > Protein center > Abcc1(Gene name) > Mouse
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  • Abcc1 (Gene name),
  • Multidrug resistance-associated protein 1 (Protein name ),  MRP1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Abcc1(Abcc1a;Abcc1b;Mdrap;Mrp);
    Protein name:
    Multidrug resistance-associated protein 1;
    Alternative:
    Leukotriene C(4) transporter(LTC4 transporter);ATP-binding cassette sub-family C member 1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    1528
    Sequence:
    50:
    MALRSFCSAD | GSDPLWDWNV | TWHTSNPDFT | KCFQNTVLTW | VPCFYLWSCF | 
    100:
    PLYFFYLSRH | DRGYIQMTHL | NKTKTALGFF | LWIICWADLF | YSFWERSQGV | 
    150:
    LRAPVLLVSP | TLLGITMLLA | TFLIQLERRK | GVQSSGIMLT | FWLVALLCAL | 
    200:
    AILRSKIISA | LKKDAHVDVF | RDSTFYLYFT | LVLVQLVLSC | FSDCSPLFSE | 
    250:
    TVHDRNPCPE | SSASFLSRIT | FWWITGMMVH | GYRQPLESSD | LWSLNKEDTS | 
    300:
    EEVVPVLVNN | WKKECDKSRK | QPVRIVYAPP | KDPSKPKGSS | QLDVNEEVEA | 
    350:
    LIVKSPHKDR | EPSLFKVLYK | TFGPYFLMSF | LYKALHDLMM | FAGPKILELI | 
    400:
    INFVNDREAP | DWQGYFYTAL | LFVSACLQTL | ALHQYFHICF | VSGMRIKTAV | 
    450:
    VGAVYRKALL | ITNAARKSST | VGEIVNLMSV | DAQRFMDLAT | YINMIWSAPL | 
    500:
    QVILALYFLW | LSLGPSVLAG | VAVMILMVPL | NAVMAMKTKT | YQVAHMKSKD | 
    550:
    NRIKLMNEIL | NGIKVLKLYA | WELAFQDKVM | SIRQEELKVL | KKSAYLAAVG | 
    600:
    TFTWVCTPFL | VALSTFAVFV | TVDERNILDA | KKAFVSLALF | NILRFPLNIL | 
    650:
    PMVISSIVQA | SVSLKRLRIF | LSHEELEPDS | IERRSIKSGE | GNSITVKNAT | 
    700:
    FTWARGEPPT | LNGITFSIPE | GALVAVVGQV | GCGKSSLLSA | LLAEMDKVEG | 
    750:
    HVTLKGSVAY | VPQQAWIQND | SLRENILFGH | PLQENYYKAV | MEACALLPDL | 
    800:
    EILPSGDRTE | IGEKGVNLSG | GQKQRVSLAR | AVYSNSDIYL | FDDPLSAVDA | 
    850:
    HVGKHIFEKV | VGPMGLLKNK | TRILVTHGIS | YLPQVDVIIV | MSGGKISEMG | 
    900:
    SYQELLDRDG | AFAEFLRTYA | NAEQDLASED | DSVSGSGKES | KPVENGMLVT | 
    950:
    DTVGKHLQRH | LSNSSSHSGD | TSQQHSSIAE | LQKAGAKEET | WKLMEADKAQ | 
    1000:
    TGQVQLSVYW | NYMKAIGLFI | TFLSIFLFLC | NHVSALASNY | WLSLWTDDPP | 
    1050:
    VVNGTQANRN | FRLSVYGALG | ILQGAAIFGY | SMAVSIGGIF | ASRRLHLDLL | 
    1100:
    YNVLRSPMSF | FERTPSGNLV | NRFSKELDTV | DSMIPQVIKM | FMGSLFSVIG | 
    1150:
    AVIIILLATP | IAAVIIPPLG | LVYFFVQRFY | VASSRQLKRL | ESVSRSPVYS | 
    1200:
    HFNETLLGVS | VIRAFEEQER | FIHQSDLKVD | ENQKAYYPSI | VANRWLAVRL | 
    1250:
    ECVGNCIVLF | AALFAVISRH | SLSAGLVGLS | VSYSLQITAY | LNWLVRMSSE | 
    1300:
    METNIVAVER | LKEYSETEKE | APWQIQETAP | PSTWPHSGRV | EFRDYCLRYR | 
    1350:
    EDLDLVLKHI | NVTIEGGEKV | GIVGRTGAGK | SSLTLGLFRI | NESAEGEIII | 
    1400:
    DGVNIAKIGL | HNLRFKITII | PQDPVLFSGS | LRMNLDPFSQ | YSDEEVWMAL | 
    1450:
    ELAHLKGFVS | ALPDKLNHEC | AEGGENLSVG | QRQLVCLARA | LLRKTKILVL | 
    1500:
    DEATAAVDLE | TDNLIQSTIR | TQFEDCTVLT | IAHRLNTIMD | YTRVIVLDKG | 
    1528:
    EVRECGAPSE | LLQQRGIFYS | MAKDAGLV
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    SMR:
    Pfam:
    KEGG:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Multidrug resistance-associated protein 1
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    E1068h
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    ELISA Kit for Mouse Multidrug resistance-associated protein 1
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    E1068r
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    ELISA Kit for Mouse Multidrug resistance-associated protein 1
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    E1068c
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    ELISA Kit for Mouse Multidrug resistance-associated protein 1
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    ELISA Kit for Mouse Multidrug resistance-associated protein 1
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    ELISA Kit for Mouse Multidrug resistance-associated protein 1
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    E1068b
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    CLIA Kit for Mouse Multidrug resistance-associated protein 1
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    U1068d
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    CLIA Kit for Mouse Multidrug resistance-associated protein 1
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    U1068m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Multidrug resistance-associated protein 1
    Cat.:
    U1068c
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Multidrug resistance-associated protein 1
    Cat.:
    U1068b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Multidrug resistance-associated protein 1
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    U1068r
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    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Mouse Multidrug resistance-associated protein 1
    Cat.:
    U1068h
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    Polyclonal Antibody for Mouse Multidrug resistance-associated protein 1
    Cat.:
    P1068Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Multidrug resistance-associated protein 1
    Polyclonal Antibody for Mouse Multidrug resistance-associated protein 1
    Polyclonal Antibody for Mouse Multidrug resistance-associated protein 1
    Polyclonal Antibody for Mouse Multidrug resistance-associated protein 1
    Cat.:
    P1068Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Multidrug resistance-associated protein 1
    Cat.:
    P1068Rb-r
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Multidrug resistance-associated protein 1
    Monoclonal Antibody for Mouse Multidrug resistance-associated protein 1
    Monoclonal Antibody for Mouse Multidrug resistance-associated protein 1
    Monoclonal Antibody for Mouse Multidrug resistance-associated protein 1
    Monoclonal Antibody for Mouse Multidrug resistance-associated protein 1
    Monoclonal Antibody for Mouse Multidrug resistance-associated protein 1
    Protein for Mouse Multidrug resistance-associated protein 1
    Protein for Mouse Multidrug resistance-associated protein 1
    Protein for Mouse Multidrug resistance-associated protein 1
    Protein for Mouse Multidrug resistance-associated protein 1
    Protein for Mouse Multidrug resistance-associated protein 1
    Protein for Mouse Multidrug resistance-associated protein 1

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    Precision
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    Linearity
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    References
    1. 1.
      "Structure and expression of the messenger RNA encoding the murine multidrug resistance protein, an ATP-binding cassette transporter."
      Stride B.D. , Valdimarsson G. , Gerlach J.H. , Wilson G.M. , Cole S.P.C. , Deeley R.G.
      Mol. Pharmacol.49:962-971(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Muscle.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Testis.
    3. 3.
      "Pharmacological characterization of the murine and human orthologs of multidrug-resistance protein in transfected human embryonic kidney cells."
      Stride B.D. , Grant C.E. , Loe D.W. , Hipfner D.R. , Cole S.P.C. , Deeley R.G.
      Mol. Pharmacol.52:344-353(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    4. 4.
      "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
      Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-878 AND SER-882;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    5. 5.
      "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
      Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUCCINYLATION [LARGE SCALE ANALYSIS] AT LYS-504;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
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